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Company profile

Denali Therapeutics Inc. Insider Trading

DNLI

Every SEC Form 4 insider trading filing for Denali Therapeutics Inc. (DNLI) since April 2023 — open-market buys and sells by directors and officers, option exercises, and cluster activity, updated as each filing is reported to the SEC. Why 2023?

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)
CIK
0001714899
Filings
124
Insiders
21
Last filing
2026-09-04
SEC EDGAR ↗Yahoo Finance ↗Finviz ↗Stock Analysis ↗

Activity summary

Recent insider activity is bearish. Over the last 30 days, insiders net sold $37K across 1 transaction.

Three year balance

Buy and sell value by quarter, Q4 23 to Q3 26. Denali Therapeutics Inc. insiders are net buyers across the period shown.

PurchasesSales
Q4 23Q1 24Q2 24Q3 24Q4 24Q1 25Q2 25Q3 25$40.0MQ4 25Q1 26Q2 26Q3 26

Bars below the rule are sales, above are purchases. Largest quarter on the chart is $40.0M.

90 day insight

Over the last 90 days, Denali Therapeutics Inc. insiders sold $108K across 2 transactions with no open-market purchases.

  • Most active insider: Nancy Thornberry with 2 transactions totaling $262K.
  • Largest single sale: $247K by Nancy Thornberry on Sep 2, 2026.
  • 60% of recent sales were pre-scheduled 10b5-1 trades — typically less informative than open-market activity.

Activity skews bearish — sales outpace buys.

Insider Transactions

Sourced from SEC EDGAR Form 4 filings. Updated hourly.

DateInsiderCompanyTypeSharesPriceValueReturn
Sep 4, 2026Peter Scott ChinDNLI
Sale
1,654$22.29$37K-7.0% 1w
Sep 2, 2026Nancy ThornberryDNLI
Sale10b5
10,824$22.85$247K-3.9% 1w
Sep 2, 2026Nancy ThornberryDNLI
Sale10b5
615$23.74$15K-3.9% 1w
Sep 1, 2026Alexander O. SchuthDNLI
Sale10b5
2,768$23.44$65K-7.5% 1w
Aug 12, 2026Ryan J. WattsDNLI
Gift
32,220——-16.0% 1m

45 more transactions hidden

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Top insiders

By total value filed.

BAKER BROS. ADVISORS LP2 filings+$40.0M
Ryan J. WattsPresident and CEO4 filings−$7.5M
Alexander O. SchuthCOFO and Secretary4 filings−$460K
Nancy ThornberryDirector2 filings−$262K
Carole HoChief Medical Officer3 filings−$21K

Institutional Ownership

Top 13F-HR holders of Denali Therapeutics Inc. as of 2026-06-30

↓ decreasing
Total reported AUM
$1.35B
QoQ change
-45.5%
Reporting period
2026-06-30
#1
Baillie Gifford & Co
CIK 0001088875
$194.9M
7.6M shares
#2
State Street Corp
CIK 0000093751
$181.3M
7.0M shares
#3
Temasek Holdings (Private) Ltd
CIK 0001021944
$180.4M
7.0M shares

Data source: quarterly 13F-HR filings — institutional holders report positions within 45 days of quarter end. Joined with insider activity above — see who's loading up institutionally while insiders are trading. Full 13F-HR API →

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Form4API, StockholmNot affiliated with the SEC or EDGAR. Data sourced from public EDGAR filings. Not investment advice.

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