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Insider profile

BAKER BROS. ADVISORS LP Insider Trading

This page tracks every SEC Form 4 filing since April 2023 by BAKER BROS. ADVISORS LP: 613 transactions in total, including 301 open-market purchases and 22 sales. Each record is parsed directly from the original filing, with amendments reconciled so a corrected filing never double-counts.

CIK
0001263508
Companies traded
2
Total filings
613
First filing
2023-03-31
Last filing
2026-08-11

Files as BAKER BROS. ADVISORS LP · SEC EDGAR ↗

Activity summary

The most recent open-market decision, on August 11, 2026, was 2 purchases totaling 2,736,340 shares ($33.0M).

Three year balance

Buy and sell value by quarter, Q4 23 to Q3 26. BAKER BROS. ADVISORS LP has been a net seller across the period shown.

PurchasesSales
$10.4BQ4 23Q1 24Q2 24Q3 24Q4 24Q1 25Q2 25Q3 25Q4 25Q1 26Q2 26Q3 26

Bars below the rule are sales, above are purchases. Largest quarter on the chart is $10.4B.

Insider insight

BAKER BROS. ADVISORS LP trades most actively in ONC, accounting for 4 of the 613 filings on record.

Track record

$1.4B
Total purchased
$902.5M
Total sold
6
0 buys · 6 sales
Net buyer
Overall direction

Most active in

ONC4 salesCELC2 sales
Filing history: Mar 2023 — Aug 2026Under a 10b5-1 plan: 0%Full history: 613 filings

Transaction History

Sourced from SEC EDGAR Form 4 filings. Updated hourly.

DateInsiderCompanyTypeSharesPriceValueReturn
Aug 11, 2026BAKER BROS. ADVISORS LPREPL
Purchase
126,394$12.06$1.52M-5.8% 1m
Aug 11, 2026BAKER BROS. ADVISORS LPREPL
Purchase
2,609,946$12.06$31.48M-5.8% 1m
Jul 14, 2026BAKER BROS. ADVISORS LPCELC
Sale
2,838,632$102.50$290.96M+3.5% 1m
Jul 14, 2026BAKER BROS. ADVISORS LPCELC
Sale
261,368$102.50$26.79M+3.5% 1m
Jun 30, 2026BAKER BROS. ADVISORS LPINCY
Award
400——+2.7% 1m

45 more transactions hidden

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Companies traded

By number of filings.

ONC4 filings
CELC2 filings

Based on the last 50 filings on file — this insider has a longer history.

Filing cadence

Filings per quarter, this window.

25.0filings / quarter, Q2 26–Q3 26

Busiest: Q2 26 (46 filings)

Quietest: Q3 26 (4 filings)

Based on the last 50 filings on file — this insider has a longer history.

Reading an insider's Form 4 history

Corporate insiders — directors, officers, and holders of more than 10% of a company's stock — must report their trades to the SEC on Form 4 within two business days. Looking at one insider's filings over time shows whether they tend to buy on the open market (a discretionary use of their own money, generally the strongest signal), sell, or simply receive and exercise equity awards as compensation.

The track record above measures how this insider's past open-market purchases performed in the months after each filing. Trades made under a pre-scheduled Rule 10b5-1 plan are flagged because they carry no timing signal. To pull any insider's full history programmatically, see the insider trading API or our guide to reading Form 4 filings.

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Form4API, StockholmNot affiliated with the SEC or EDGAR. Data sourced from public EDGAR filings. Not investment advice.

Scorecard

89%
Buys positive after 3m
+26.1%
Avg return at 3m
+25.5%
Median return at 3m
261
Scored buys
Best buy: CELC+83.7% 3m (Sep 2025)Worst buy: BCYC-40.0% 3m (Dec 2024)

Absolute post-filing return, not market-adjusted · min. 5 matured open-market buys

See top insiders by track record →

Related insiders

Other insiders filing on ONC.

John OylerChief Executive OfficerChan Henry LeeSVP, General CounselXiaobin WuPresident and COO