// company-profile
Spero Therapeutics, Inc.
SPROExchangeNasdaqSectorPharmaceutical PreparationsInc.DEFilings57Insiders13
// api This Spero Therapeutics, Inc. insider-trading data is served live by the Form4API insider trading API. Get the same data via API.
// activity-summary
No insider transactions in the last 30 days.
// 90-day insight
Over the last 90 days, Spero Therapeutics, Inc. insiders sold $63K across 1 transaction with no open-market purchases.
- Most active insider: Rajavelu Esther with 1 transaction totaling $63K.
- Largest single sale: $63K by Rajavelu Esther on May 4, 2026.
Activity skews bearish — sales outpace buys.
Institutional Ownership
Top 13F-HR holders of Spero Therapeutics, Inc. as of 2026-03-31
Total reported AUM
$47.4M
QoQ change
-1.4%
Reporting period
2026-03-31
#1
GSK plc
CIK 1131399
$21.5M
9.2M shares
#2
Pfizer Inc
CIK 78003
$5.5M
2.4M shares
#3
VANGUARD CAPITAL MANAGEMENT LLC
CIK 2100119
$4.2M
1.8M shares
Data source: SEC Form 13F-HR filings. Joined with insider activity above — see who's loading up institutionally while insiders are trading. Full 13F-HR API →
Insider Transactions
Sourced from SEC EDGAR Form 4 filings. Updated hourly.
| Date | Insider | Company | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| May 4, 2026 | Rajavelu Esther | SPRO | Sale | 25,240 | $2.51 | $63K |
| Feb 6, 2026 | Keutzer Timothy | SPRO | Sale | 18,652 | $2.36 | $44K |
| Feb 6, 2026 | Rajavelu Esther | SPRO | Sale | 50,816 | $2.36 | $120K |
| Feb 6, 2026 | Rajavelu Esther | SPRO | Sale | 37,101 | $2.36 | $88K |
| Feb 4, 2026 | Keutzer Timothy | SPRO | Sale | 3,471 | $2.24 | $8K |
45 more transactions hidden
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