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Company profile

Septerna, Inc. Insider Trading

SEPN

Every SEC Form 4 insider trading filing for Septerna, Inc. (SEPN) since April 2023 — open-market buys and sells by directors and officers, option exercises, and cluster activity, updated as each filing is reported to the SEC. Why 2023?

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
CIK
0001984086
Filings
58
Insiders
26
Last filing
2026-08-12
SEC EDGAR ↗Yahoo Finance ↗Finviz ↗Stock Analysis ↗

Activity summary

Recent insider activity is bullish. Over the last 30 days, 8 insiders purchased shares versus 2 sales. Buying was led by Bhatt Elizabeth.

Three year balance

Buy and sell value by quarter, Q4 24 to Q3 26. Septerna, Inc. insiders are net buyers across the period shown.

Q4 24Q1 25Q2 25Q3 25Q4 25Q1 26Q2 26Q3 26

Bars below the rule are sales, above are purchases. Largest quarter on the chart is $86.8M.

90 day insight

Over the last 90 days, Septerna, Inc. insiders bought $371K (34 transactions) and sold $63.5M (2 transactions).

  • Most active insider: Long Daniel D. with 16 transactions totaling $862K.
  • Largest single sale: $31.7M by Ra Capital Management, L.p. on Aug 12, 2026.
  • 88% of recent sales were pre-scheduled 10b5-1 trades — typically less informative than open-market activity.

Activity skews bullish — buys outpace sales.

Insider Transactions

Sourced from SEC EDGAR Form 4 filings. Updated hourly.

DateInsiderCompanyTypeSharesPriceValue1d1w1m3m6m
Aug 12, 2026Third Rock Ventures V, L.P.SEPN
Sale10b5
141$51.08$7K+1.6%-10.1%———
Aug 12, 2026Ra Capital Management, L.p.SEPN
Sale
746,500$42.50$31.73M+1.6%-10.1%———
Aug 12, 2026Third Rock Ventures V, L.P.SEPN
Sale10b5
147,059$50.27$7.39M+1.6%-10.1%———
Aug 12, 2026Ra Capital Management, L.p.SEPN
Sale
746,500$42.50$31.73M+1.6%-10.1%———
Aug 11, 2026Bhatt ElizabethSEPN
Sale10b5
25,000$44.00$1.10M-1.4%-9.8%———

45 more transactions hidden

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Top insiders

By total value filed.

Ra Capital Management, L.p.2 filings−$63.5M
Third Rock Ventures V, L.P.2 filings−$7.4M
Bhatt ElizabethPresident and COO5 filings−$1.1M
Long Daniel D.SVP, Drug Discovery11 filings−$662K
Shaikhly SamiraChief People Officer9 filings−$330K

Institutional Ownership

Top 13F-HR holders of Septerna, Inc. as of 2026-06-30

↓ decreasing
Total reported AUM
$453.8M
QoQ change
-58.3%
Reporting period
2026-06-30
#1
Trv GP V, LLC
CIK 0001990717
$208.2M
6.2M shares
#2
Trv GP VI, LLC
CIK 0001990716
$141.0M
4.2M shares
#3
BlackRock, Inc.
CIK 0002012383
$36.4M
1.1M shares

Data source: quarterly 13F-HR filings — institutional holders report positions within 45 days of quarter end. Joined with insider activity above — see who's loading up institutionally while insiders are trading. Full 13F-HR API →

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Form4API, StockholmNot affiliated with the SEC or EDGAR. Data sourced from public EDGAR filings. Not investment advice.

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