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Company profile

Karyopharm Therapeutics Inc. Insider Trading

KPTI

Every SEC Form 4 insider trading filing for Karyopharm Therapeutics Inc. (KPTI) since April 2023 — open-market buys and sells by directors and officers, option exercises, and cluster activity, updated as each filing is reported to the SEC. Why 2023?

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
CIK
0001503802
Filings
145
Insiders
16
Last filing
2026-09-01
SEC EDGAR ↗Yahoo Finance ↗Finviz ↗Stock Analysis ↗

Activity summary

Recent insider activity is bearish. Over the last 30 days, insiders net sold $38 across 1 transaction.

Three year balance

Buy and sell value by quarter, Q4 23 to Q3 26. Karyopharm Therapeutics Inc. insiders were net sellers in every quarter shown.

PurchasesSales
Q4 23Q1 24$1.7MQ2 24Q3 24Q4 24Q1 25Q2 25Q3 25Q4 25Q1 26Q2 26Q3 26

Bars below the rule are sales, above are purchases. Largest quarter on the chart is $1.7M.

90 day insight

Over the last 90 days, Karyopharm Therapeutics Inc. insiders sold $1K across 2 transactions with no open-market purchases.

  • Most active insider: Stuart Poulton with 1 transaction totaling $1K.
  • Largest single sale: $1K by Stuart Poulton on Jul 28, 2026.

Activity skews bearish — sales outpace buys.

Insider Transactions

Sourced from SEC EDGAR Form 4 filings. Updated hourly.

DateInsiderCompanyTypeSharesPriceValueReturn
Sep 1, 2026Kristin AbateKPTI
Sale
19$2.02$38-9.5% 1w
Jul 28, 2026Stuart PoultonKPTI
Sale
189$7.10$1K-72.2% 1m
May 21, 2026Chen SchorKPTI
Award
15,508——-78.6% 3m
May 21, 2026Christy J. OligerKPTI
Award
15,508——-78.6% 3m
May 21, 2026Garen G BohlinKPTI
Award
15,508——-78.6% 3m

45 more transactions hidden

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Top insiders

By total value filed.

Richard A. PaulsonPresident and CEO3 filings−$145K
Stuart PoultonEVP, Chief Development Officer5 filings−$59K
Reshma RangwalaEVP & Chief Medical Officer4 filings−$58K
Sohanya Roshan ChengEVP & Chief Commercial Officer3 filings−$48K
Michael ManoSVP, General Counsel&Secretary2 filings−$36K

Institutional Ownership

Top 13F-HR holders of Karyopharm Therapeutics Inc. as of 2026-06-30

— stable
Total reported AUM
$18.8M
QoQ change
—
Reporting period
2026-06-30
#1
BlackRock, Inc.
CIK 0002012383
$7.8M
793K shares
#2
BlackRock, Inc.
CIK 0002012383
$4.2M
435K shares
#3
State Street Corp
CIK 0000093751
$3.2M
326K shares

Data source: quarterly 13F-HR filings — institutional holders report positions within 45 days of quarter end. Joined with insider activity above — see who's loading up institutionally while insiders are trading. Full 13F-HR API →

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Form4API, StockholmNot affiliated with the SEC or EDGAR. Data sourced from public EDGAR filings. Not investment advice.

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