// company-profile

Ionis Pharmaceuticals Inc

IONS
ExchangeNasdaqSectorPharmaceutical PreparationsInc.CAFilings330Insiders24
// api This Ionis Pharmaceuticals Inc insider-trading data is served live by the Form4API insider trading API. Get the same data via API.

// activity-summary

Recent insider activity is bullish. Over the last 30 days, 14 insiders purchased shares (net $3.7M). Buying was led by Kordasiewicz Holly B..

// 90-day insight

Over the last 90 days, Ionis Pharmaceuticals Inc insiders bought $8.1M (35 transactions) and sold $860K (3 transactions).

  • Most active insider: LOSCALZO JOSEPH with 14 transactions totaling $9.6M.
  • Largest single sale: $4.5M by LOSCALZO JOSEPH on May 4, 2026.
  • 80% of recent sales were pre-scheduled 10b5-1 trades — typically less informative than open-market activity.

Activity skews bullish — buys outpace sales.

Institutional Ownership

Top 13F-HR holders of Ionis Pharmaceuticals Inc as of 2026-03-31

— stable
Total reported AUM
$11.49B
QoQ change
-1.4%
Reporting period
2026-03-31
#1
Capital World Investors
CIK 1422849
$1.59B
21.2M shares
#2
FMR LLC
CIK 315066
$1.02B
13.5M shares
#3
FMR LLC
CIK 315066
$827.0M
11.0M shares

Data source: SEC Form 13F-HR filings. Joined with insider activity above — see who's loading up institutionally while insiders are trading. Full 13F-HR API →

Insider Transactions

Sourced from SEC EDGAR Form 4 filings. Updated hourly.

DateInsiderCompanyTypeSharesPriceValue
Jun 15, 2026BERTHELSEN SPENCER RIONS
Option Exercise
8,000$0.00$0K
Jun 15, 2026BERTHELSEN SPENCER RIONS
Option Exercise
8,000$24.42$195K
Jun 15, 2026BERTHELSEN SPENCER RIONS
Sale10b5
8,000$73.49$588K
Jun 12, 2026Kordasiewicz Holly B.IONS
Option Exercise
19,895$56.78$1.13M
Jun 12, 2026Kordasiewicz Holly B.IONS
Option Exercise
21,000$0.00$0K

45 more transactions hidden

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