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Company profile

Alnylam Pharmaceuticals, Inc. Insider Trading

ALNY

Every SEC Form 4 insider trading filing for Alnylam Pharmaceuticals, Inc. (ALNY) since April 2023: open-market buys and sells by directors and officers, option exercises, and cluster activity, updated as each filing is reported to the SEC. Why 2023?

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
CIK
0001178670
Filings
163
Insiders
24
Last filing
2026-09-19
SEC EDGAR ↗Yahoo Finance ↗Finviz ↗Stock Analysis ↗

Activity summary

Recent insider activity is bullish. Over the last 30 days, 1 insider purchased shares. Buying was led by Yvonne Greenstreet.

Three year balance

Buy and sell value by quarter, Q4 23 to Q3 26. Alnylam Pharmaceuticals, Inc. insiders are net sellers across the period shown.

PurchasesSales
Q4 23Q1 24Q2 24Q3 24Q4 24Q1 25Q2 25$35.5MQ3 25Q4 25Q1 26Q2 26Q3 26

Bars below the rule are sales, above are purchases. Largest quarter on the chart is $35.5M.

90 day insight

Over the last 90 days, Alnylam Pharmaceuticals, Inc. insiders bought $0 across 1 transaction with no open-market sales.

  • Most active insider: Yvonne Greenstreet with 1 transaction totaling $0.

Activity skews bullish: buys outpace sales.

Insider Transactions

Sourced from SEC EDGAR Form 4 filings. Updated hourly.

DateInsiderCompanyTypeSharesPriceValueReturn
Sep 19, 2026Yvonne GreenstreetALNY
Award
107——Pending
Jun 1, 2026David E I PyottALNY
Option Exercise10b5
3,830——-8.6% 3m
Jun 1, 2026David E I PyottALNY
Sale10b5
921$297.71$274K-8.6% 3m
Jun 1, 2026David E I PyottALNY
Sale10b5
1,175$298.91$351K-8.6% 3m
Jun 1, 2026David E I PyottALNY
Sale10b5
1,222$299.87$366K-8.6% 3m

45 more transactions hidden

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Top insiders

By total value filed.

Melissa McLaughlinChief Human Resources Officer14 filings−$1.3M
David E I PyottDirector5 filings−$1.1M
Amy W Schulman10% owner1 filing+$790K
Pushkal GargCMO & EVP Dev & Med Affairs3 filings−$616K
Kevin Joseph FitzgeraldCSO & EVP, Head of Research4 filings−$213K

Institutional Ownership

Top 13F-HR holders of Alnylam Pharmaceuticals, Inc. as of 2026-06-30

↓ decreasing
Total reported AUM
$7.24B
QoQ change
-79.9%
Reporting period
2026-06-30
#1
BlackRock, Inc.
CIK 0002012383
$1.26B
4.2M shares
#2
State Street Corp
CIK 0000093751
$1.07B
3.6M shares
#3
BlackRock, Inc.
CIK 0002012383
$1.03B
3.4M shares

Data source: quarterly 13F-HR filings: institutional holders report positions within 45 days of quarter end. Joined with insider activity above: see who's loading up institutionally while insiders are trading. Full 13F-HR API →

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Form4API, StockholmNot affiliated with the SEC or EDGAR. Data sourced from public EDGAR filings. Not investment advice.

Congressional Trading

Disclosed ALNY trades under the STOCK Act

Total trades
1
Purchases
0
Sales
1
Jefferson Shreve
Republican · House · IN
0 buys
1 sell

Sourced from U.S. House Clerk periodic transaction reports (House coverage only). Trade counts reflect disclosed filings only. The STOCK Act allows up to 45 days between a trade and its disclosure, so this reflects recent disclosures, not real-time trading. Full congressional trading API →

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